Commonly reported side effects of niacin include: pruritus, nausea, and flushing. Other side effects include: skin rash, and vomiting. Continue reading for a comprehensive list of adverse effects.
Applies to niacin: oral tablets.
Side effects include:
Flushing (e.g., warmth, redness, itching and/or tingling), headache, pain, abdominal pain, diarrhea, dyspepsia, nausea, vomiting, rhinitis, pruritus, rash.
For Healthcare Professionals
Applies to niacin: compounding powder, oral capsule, oral capsule extended release, oral liquid, oral tablet, oral tablet extended release.
Very common (10% or more): Flushing (i.e., warmth, redness, itching, and/or tingling) (up to 88%)
Frequency not reported: Tachycardia, palpitations, atrial fibrillation, other cardiac arrhythmias, syncope, hypotension, postural hypotension[Ref]
Common (1% to 10%): Rash, pruritus
Frequency not reported: Sweating, skin burning sensation, maculopapular rash, dry skin
Postmarketing reports: Skin discoloration[Ref]
Very common (10% or more): Diarrhea (up to 14%), nausea (up to 11%)
Common (1% to 10%): Vomiting
Frequency not reported: Peptic ulcers, eructation, flatulence[Ref]
Postmarketing reports: Slight reductions in platelet counts, prothrombin time prolonged[Ref]
Postmarketing reports: Hypersensitivity reactions (e.g., anaphylaxis, angioedema, urticaria, flushing, dyspnea, tongue edema, larynx edema, face edema, peripheral edema, laryngismus, vesiculobullous rash)[Ref]
Postmarketing reports: Hepatitis, jaundice[Ref]
Frequency not reported: Decreased glucose tolerance, gout[Ref]
Frequency not reported: Myalgia, myopathy[Ref]
Frequency not reported: Dizziness, syncope
Postmarketing reports: Migraine, asthenia, paresthesia[Ref]
Postmarketing reports: Blurred vision, macular edema[Ref]
Postmarketing reports: Insomnia, nervousness[Ref]
Frequency not reported: Chills, edema[Ref]
Common (1% to 10%): Cough increased
Frequency not reported: Dyspnea[Ref]