Note: This document contains side effect information about tezepelumab. Some dosage forms listed on this page may not apply to the brand name Tezspire.
Applies to tezepelumab: subcutaneous solution.
Serious side effects of Tezspire
Along with its needed effects, tezepelumab (the active ingredient contained in Tezspire) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor immediately if any of the following side effects occur while taking tezepelumab:
Incidence not known
- Burning, dry, or itching eyes
- chest tightness
- discharge, excessive tearing
- fast heartbeat
- hives, itching, skin rash
- hoarseness
- irritation
- joint pain, stiffness, or swelling
- lightheadedness, dizziness, or fainting
- redness, pain, swelling of the eye, eyelid, or inner lining of the eyelid
- redness of the skin
- swelling of the eyelids, face, lips, mouth, tongue, hands, or feet
- trouble breathing
Other side effects of Tezspire
Some side effects of tezepelumab may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.
Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:
Less common
- Back pain
- body aches or pain
- cough
- difficulty in moving
- dryness or soreness of the throat
- fever
- muscle pain or stiffness
- redness, pain, or itching at the injection site
- stuffy or runny nose
- tender, swollen glands in the neck
- trouble swallowing
- voice changes
For Healthcare Professionals
Applies to tezepelumab: subcutaneous solution.
General
The most reported adverse reactions have included pharyngitis, arthralgia, and back pain.[Ref]
Respiratory
Common (1% to 10%): Pharyngitis (including bacterial, streptococcal, and viral pharyngitis)
Immunologic
Common (1% to 10%): Anti-drug antibodies
Musculoskeletal
Common (1% to 10%): Arthralgia, back pain
Local
Common (1% to 10%): Injection site reactions (e.g., injection site erythema, injection site swelling, injection site pain)
