Note: This document contains side effect information about dexamethasone / tobramycin ophthalmic. Some dosage forms listed on this page may not apply to the brand name TobraDex.

Applies to dexamethasone/tobramycin ophthalmic: ophthalmic ointment, ophthalmic suspension.

Serious side effects of TobraDex

Along with its needed effects, dexamethasone/tobramycin ophthalmic may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor as soon as possible if any of the following side effects occur while taking dexamethasone / tobramycin ophthalmic:

Less common

• Itching and swelling of eyelid
• redness of eye

Rare

• Delayed wound healing
• eye pain
• gradual blurring or loss of vision

For Healthcare Professionals

Applies to dexamethasone / tobramycin ophthalmic: ophthalmic ointment, ophthalmic suspension.

Hypersensitivity

Frequency not reported: Hypersensitivity^[Ref]

Ocular

Uncommon (0.1% to 1%): Eye pain, eye pruritus, ocular discomfort, ocular hypertension, conjunctival edema, increased intraocular pressure, eye irritation

Rare (less than 0.1%): Keratitis, eye allergy, blurred vision, dry eye, ocular hyperemia

Frequency not reported: Eyelid edema, erythema of the eyelid, mydriasis, increased lacrimation

Dexamethasone:

-Common (1% to 10%): Ocular hyperemia, erythema of eyelid, abnormal sensation in eye, eye pain

-Uncommon (0.1% to 1%): Eye pruritus, ocular discomfort, eye allergy, eyelid edema, conjunctivitis, glare, increased lacrimation, keratitis

-Frequency not reported: Optic nerve damage, posterior subcapsular cataract formation, fungal infections of the cornea, bacterial ocular infection

Tobramycin:

-Common (1% to 10%):

-Frequency not reported: Conjunctival erythema, ocular toxicity^[Ref]

Other

Frequency not reported: Swelling face^[Ref]

Dermatologic

Frequency not reported: Rash, pruritus^[Ref]

General

The most commonly reported side effects were eye irritation, ocular hyperemia, erythema of eyelid, abnormal sensation in eye, ocular hyperemia, and eye pain.^[Ref]

Gastrointestinal

Rare (less than 0.1%): Dysgeusia

Frequency not reported: Nausea, abdominal discomfort^[Ref]

Immunologic

Dexamethasone:

-Frequency not reported: Delayed wound healing^[Ref]

Nervous system

Uncommon (0.1% to 1%): Headache

Frequency not reported: Dizziness^[Ref]

Respiratory

Uncommon (0.1% to 1%): Rhinorrhea, laryngospasm^[Ref]