Miscellaneous antihyperlipidemic agents
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Leqvio Dosage

Drug Detail:Leqvio (Inclisiran)

Generic Name: INCLISIRAN SODIUM 284mg in 1.5mL

Dosage Form: injection, solution

Drug Class: Miscellaneous antihyperlipidemic agents

Contents
Uses Warnings Before Taking Dosage Side effects Interactions FAQ

2.1 Recommended Dosage

  • The recommended dosage of LEQVIO, in combination with statin therapy, is 284 mg administered as a single subcutaneous injection initially, again at 3 months, and then every 6 months.
  • If a planned dose is missed by less than 3 months, administer LEQVIO and maintain dosing according to the patient’s original schedule.
  • If a planned dose is missed by more than 3 months, restart with a new dosing schedule - administer LEQVIO initially, again at 3 months, and then every 6 months.
  • Assess LDL-C when clinically indicated. The LDL-lowering effect of LEQVIO may be measured as early as 30 days after initiation and anytime thereafter without regard to timing of the dose.

2.2 Important Administration Instructions

  • LEQVIO should be administered by a healthcare professional.
  • Inject LEQVIO subcutaneously into the abdomen, upper arm, or thigh. Do not inject in areas of active skin disease or injury, such as sunburns, skin rashes, inflammation, or skin infections.
  • Inspect LEQVIO visually before use. It should appear clear and colorless to pale yellow. Do not use if particulate matter or discoloration is seen.
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