Uses of Fasenra:

• It is used to treat asthma.
• Do not use Fasenra (benralizumab prefilled syringes) to treat an asthma attack. Use a rescue inhaler. Talk with your doctor.

What do I need to tell my doctor BEFORE I take Fasenra?

• If you are allergic to Fasenra (benralizumab prefilled syringes); any part of Fasenra (benralizumab prefilled syringes); or any other drugs, foods, or substances. Tell your doctor about the allergy and what signs you had.
• If you have or may have a worm infection.

This is not a list of all drugs or health problems that interact with Fasenra (benralizumab prefilled syringes).

Tell your doctor and pharmacist about all of your drugs (prescription or OTC, natural products, vitamins) and health problems. You must check to make sure that it is safe for you to take Fasenra (benralizumab prefilled syringes) with all of your drugs and health problems. Do not start, stop, or change the dose of any drug without checking with your doctor.

What are some things I need to know or do while I take Fasenra?

• Tell all of your health care providers that you take Fasenra (benralizumab prefilled syringes). This includes your doctors, nurses, pharmacists, and dentists.
• Call your doctor right away if your breathing problems get worse, if your rescue inhaler does not work as well, or if you need to use your rescue inhaler more often.
• Allergic reactions have happened with Fasenra (benralizumab prefilled syringes). Most of the time, allergic reactions happen within hours after Fasenra (benralizumab prefilled syringes) was given. Sometimes, they can happen days after Fasenra (benralizumab prefilled syringes) was given. Talk with the doctor.
• If you are switching to Fasenra (benralizumab prefilled syringes) from a steroid, do not stop taking the steroid all of a sudden. The dose of the steroid may need to be slowly lowered to avoid side effects. Talk with the doctor.
• Tell your doctor if you are pregnant, plan on getting pregnant, or are breast-feeding. You will need to talk about the benefits and risks to you and the baby.

How is this medicine (Fasenra) best taken?

Use Fasenra (benralizumab prefilled syringes) as ordered by your doctor. Read all information given to you. Follow all instructions closely.

• It is given as a shot into the fatty part of the skin on the top of the thigh, belly area, or upper arm.

What do I do if I miss a dose?

• Call your doctor to find out what to do.

What are some side effects that I need to call my doctor about right away?

WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Tell your doctor or get medical help right away if you have any of the following signs or symptoms that may be related to a very bad side effect:

• Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing, swallowing, or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat.
• Dizziness or passing out.
• Trouble breathing that is new or worse.

What are some other side effects of Fasenra?

All drugs may cause side effects. However, many people have no side effects or only have minor side effects. Call your doctor or get medical help if any of these side effects or any other side effects bother you or do not go away:

• Headache.
• Sore throat.

These are not all of the side effects that may occur. If you have questions about side effects, call your doctor. Call your doctor for medical advice about side effects.

You may report side effects to the FDA at 1-800-332-1088. You may also report side effects at https://www.fda.gov/medwatch.

If OVERDOSE is suspected:

If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.

How do I store and/or throw out Fasenra?

• If you need to store Fasenra (benralizumab prefilled syringes) at home, talk with your doctor, nurse, or pharmacist about how to store it.

Consumer Information Use and Disclaimer

• If your symptoms or health problems do not get better or if they become worse, call your doctor.
• Do not share your drugs with others and do not take anyone else's drugs.
• Keep all drugs in a safe place. Keep all drugs out of the reach of children and pets.
• Throw away unused or expired drugs. Do not flush down a toilet or pour down a drain unless you are told to do so. Check with your pharmacist if you have questions about the best way to throw out drugs. There may be drug take-back programs in your area.
• Some drugs may have another patient information leaflet. Check with your pharmacist. If you have any questions about Fasenra (benralizumab prefilled syringes), please talk with your doctor, nurse, pharmacist, or other health care provider.
• If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.

Frequently asked questions

• What are monoclonal antibodies?
• Does Fasenra weaken your immune system?
• How long does Fasenra take to work?
• What is Fasenra used for and how does it work?
• What type of asthma is Fasenra used to treat?

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