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Home > Drugs > Treatments > Rheumatoid Arthritis

Medications for Rheumatoid Arthritis

Other names: Arthritis; Arthritis, Rheumatoid; RA

Rheumatoid arthritis is a long-term inflammatory condition that can affect the joints and other tissues and organs in the body.

What causes Rheumatoid Arthritis?

Rheumatoid arthritis (RA) is considered an autoimmune condition, which means it is caused by your immune system making antibodies which attack your tissue.

Experts are not sure why the immune system in some people does this, but they have identified certain risk factors that make some people more likely than others to develop RA. These include:

  • Smoking
  • Hormones: Women are more likely to develop RA than men
  • Having a family history of RA: Some evidence that RA can run in families

Some research suggests triggers, such as infection, trauma, or injury may kick off RA; however, none of these have been proven.

What are the symptoms of Rheumatoid Arthritis?

The main symptoms of RA are joint pain, swelling, and stiffness. Usually, symptoms develop gradually over several weeks, but in some people, symptoms develop rapidly.

The small joints of the hand and feet (such as the wrists, fingers, knees, toes, and ankles) are usually the first to become affected. Stiffness is usually worse first thing in the morning or after periods of inactivity and may make movement difficult. RA usually affects the joints on both sides of the body equally.

The pain is typically described as throbbing and aching. Joint stiffness is usually worse in the morning but still tends to persist, unlike stiffness caused by osteoarthritis which tends to wear off after about 30 minutes. Because the tissue inside the joints is affected, joints may look swollen and feel hot and tender to the touch. Some people develop firm swellings under the skin, called nodules,  around affected joints.
Joint and bone destruction can occur over time if the disease process is not well-controlled.

Patients may also lack energy and have experience fevers, sweating, a poor appetite, and weight loss. Other symptoms may occur depending on what other parts of the body are affected, for example, dry eyes, or heart or lung problems.

How is Rheumatoid arthritis diagnosed?

If you develop any symptoms suggestive of RA, see your doctor. Your doctor will complete a physical exam checking your joints for warmth or redness, and also check your reflexes and joint strength.

Other tests that may be conducted include:

  • Blood tests
  • C-reactive protein (CRC)
  • Rheumatoid Factor test
  • X-rays
  • An MRI.

How is Rheumatoid Arthritis treated?

Rheumatoid arthritis usually requires lifelong treatment with:

  • Medications
  • Physical therapy
  • Targeted home exercises
  • Health education
  • Possibly surgery.


Early, aggressive treatment of rheumatoid arthritis can delay joint destruction. 

Drugs used to treat Rheumatoid Arthritis

Name Drug Class Updated
Baricitinib Antirheumatics 16-Aug-2023
Camphor, menthol, and methyl salicylate (topical) Topical rubefacient 16-Aug-2023
Chondroitin Nutraceutical products 16-Aug-2023
Enbrel sureclick Antirheumatics 16-Aug-2023
Flurbiprofen Nonsteroidal anti-inflammatory drugs 17-Aug-2023
Piroxicam Nonsteroidal anti-inflammatory drugs 16-Aug-2023
Methyl salicylate topical Topical rubefacient 16-Aug-2023
Devil's claw Herbal products 15-Aug-2023
Bengay arthritis Topical rubefacient 15-Aug-2023
Anakinra Antirheumatics 15-Aug-2023
Sarilumab Antirheumatics 15-Aug-2023
Salsalate Salicylates 15-Aug-2023
Salonpas arthritis pain Topical rubefacient 15-Aug-2023
Penicillamine Antirheumatics 15-Aug-2023
Interferon gamma-1b Interferons 14-Aug-2023
Interferon gamma (monograph) Drugs 14-Aug-2023
Fordagel (topical) Topical rubefacient 14-Aug-2023
Fenoprofen Nonsteroidal anti-inflammatory drugs 14-Aug-2023
Esomeprazole and naproxen Nonsteroidal anti-inflammatory drugs 14-Aug-2023
Cold and hot pain relief Topical rubefacient 14-Aug-2023
Coats aloe analgesic liniment Topical rubefacient 14-Aug-2023
Neuroxa kit (topical) Topical rubefacient 14-Aug-2023
Meclofenamate Nonsteroidal anti-inflammatory drugs 13-Aug-2023
Famotidine and ibuprofen Nonsteroidal anti-inflammatory drugs 13-Aug-2023
Diflunisal Nonsteroidal anti-inflammatory drugs 13-Aug-2023
Diclofenac and misoprostol Nonsteroidal anti-inflammatory drugs 13-Aug-2023
Alemtuzumab CD52 monoclonal antibodies 13-Aug-2023
Acetaminophen and tramadol Narcotic analgesic combinations 13-Aug-2023
Abatacept Antirheumatics 13-Aug-2023
Vallegel prep (topical) Topical rubefacient 12-Aug-2023
Tofacitinib Antirheumatics 12-Aug-2023
Slippery elm Herbal products 12-Aug-2023
Reallief gel-i (topical) Topical rubefacient 12-Aug-2023
Oxaprozin Nonsteroidal anti-inflammatory drugs 11-Aug-2023
Nabumetone Nonsteroidal anti-inflammatory drugs 11-Aug-2023
Leflunomide Antirheumatics 11-Aug-2023
Icy hot Topical rubefacient 11-Aug-2023
Golimumab TNF alfa inhibitors 11-Aug-2023
Chaparral Herbal products 11-Aug-2023
Auranofin Antirheumatics 11-Aug-2023
Painzone Topical rubefacient 07-Aug-2023
Mentholatum pain patch Topical rubefacient 07-Aug-2023
Mentholatum pain gel Topical rubefacient 07-Aug-2023
Satogesic pad Topical rubefacient 07-Aug-2023
Satogesic hot gel Topical rubefacient 07-Aug-2023
Pain stick sports formula Topical rubefacient 07-Aug-2023
Pain stick arthritis formula Topical rubefacient 07-Aug-2023
Lortab elixir Narcotic analgesic combinations 07-Aug-2023
Duraflex comfort Topical rubefacient 07-Aug-2023
Deep down pain relief Topical rubefacient 07-Aug-2023
Arthricare cream Topical rubefacient 07-Aug-2023
Therapeutic pain relief Topical rubefacient 07-Aug-2023
Actemra actpen Interleukin inhibitors 05-Aug-2023
Simponi smartject TNF alfa inhibitors 05-Aug-2023
Simponi aria TNF alfa inhibitors 05-Aug-2023
Zamicet Narcotic analgesic combinations 14-Jul-2023
Xodol Narcotic analgesic combinations 14-Jul-2023
Vioxx Cox-2 inhibitors 14-Jul-2023
Vimovo Nonsteroidal anti-inflammatory drugs 14-Jul-2023
Satogesic Topical rubefacient 14-Jul-2023
Salonpas pain patch Topical rubefacient 14-Jul-2023
Ridaura Antirheumatics 14-Jul-2023
Reditrex (injection) Drugs 14-Jul-2023
Rasuvo (injection) Antimetabolites 14-Jul-2023
Prevacid naprapac Nonsteroidal anti-inflammatory drugs 14-Jul-2023
Otrexup (injection) Antimetabolites 13-Jul-2023
Optiflex-g Nutraceutical products 13-Jul-2023
Optiflex-c Nutraceutical products 13-Jul-2023
Olumiant Antirheumatics 13-Jul-2023
Nalfon Nonsteroidal anti-inflammatory drugs 13-Jul-2023
Mentholatum deep heating Topical rubefacient 13-Jul-2023
Lortab Narcotic analgesic combinations 13-Jul-2023
Lodine Nonsteroidal anti-inflammatory drugs 13-Jul-2023
Hycet Narcotic analgesic combinations 13-Jul-2023
Heet triple action Topical rubefacient 13-Jul-2023
Gordogesic Topical rubefacient 13-Jul-2023
Genicin Nutraceutical products 13-Jul-2023
Feldene Nonsteroidal anti-inflammatory drugs 13-Jul-2023
Exocaine plus Topical rubefacient 13-Jul-2023
Eucalyptamint Topical rubefacient 13-Jul-2023
Erelzi sensoready pen Antirheumatics 13-Jul-2023
Erelzi prefilled syringe Antirheumatics 13-Jul-2023
Duexis Nonsteroidal anti-inflammatory drugs 13-Jul-2023
Depen Antirheumatics 13-Jul-2023
Daypro Nonsteroidal anti-inflammatory drugs 13-Jul-2023
Cuprimine Antirheumatics 13-Jul-2023
Castiva cooling Topical rubefacient 13-Jul-2023
Boroleum Topical rubefacient 13-Jul-2023
Bextra Cox-2 inhibitors 13-Jul-2023
Arthrotec Nonsteroidal anti-inflammatory drugs 12-Jul-2023
Arava Antirheumatics 12-Jul-2023
Xeljanz Antirheumatics 12-Jul-2023
Vicodin Narcotic analgesic combinations 12-Jul-2023
Simponi TNF alfa inhibitors 12-Jul-2023
Relafen Nonsteroidal anti-inflammatory drugs 11-Jul-2023
Plaquenil Antimalarial quinolines 11-Jul-2023
Orencia Antirheumatics 11-Jul-2023
Norco Narcotic analgesic combinations 11-Jul-2023
Mobic Nonsteroidal anti-inflammatory drugs 11-Jul-2023
Kineret Antirheumatics 11-Jul-2023
Kevzara Antirheumatics 11-Jul-2023
Acetaminophen and hydrocodone Narcotic analgesic combinations 10-Jul-2023
Glucosamine Nutraceutical products 10-Jul-2023
Etodolac Nonsteroidal anti-inflammatory drugs 10-Jul-2023
Enbrel Antirheumatics 10-Jul-2023
Abatacept Antirheumatics 29-Aug-2023
Actemra Interleukin inhibitors 10-Jul-2023
Tofidence Drugs 02-Oct-2023
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