Drug Detail:Amiloride (Amiloride [ a-mil-o-ride ])
Drug Class: Potassium-sparing diuretics
Amiloride Levels and Effects while Breastfeeding
Summary of Use during Lactation
No information is available on the use of amiloride during breastfeeding, so an alternate drug may be preferred.
Drug Levels
Relevant published information was not found as of the revision date.
Effects in Breastfed Infants
Relevant published information was not found as of the revision date.
Effects on Lactation and Breastmilk
Intense diuresis can suppress lactation;[1,2] however, it is unlikely that amiloride alone is sufficiently potent to cause this effect.
Alternate Drugs to Consider
Spironolactone
References
- 1.
-
Healy M. Suppressing lactation with oral diuretics. Lancet. 1961;1:1353–4. [CrossRef]
- 2.
-
Cominos DC, Van Der Walt A, Van Rooyen AJ. Suppression of postpartum lactation with furosemide. S Afr Med J 1976;50:251-2. PMID: 3858. [PubMed: 3858]
Substance Identification
Substance Name
Amiloride
CAS Registry Number
2609-46-3
Drug Class
Breast Feeding
Lactation
Diuretics
- 1.
-
Healy M. Suppressing lactation with oral diuretics. Lancet 1961;1:1353-4. doi:10.1016/S0140-6736(61)90289-6
- 2.
-
Cominos DC, Van Der Walt A, Van Rooyen AJ. Suppression of postpartum lactation with furosemide. S Afr Med J 1976;50:251-2. PMID: 3858
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Disclaimer: Information presented in this database is not meant as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. The U.S. government does not warrant or assume any liability or responsibility for the accuracy or completeness of the information on this Site.
- Drug Levels and Effects
- Substance Identification
