Drug Detail:Basiliximab (Basiliximab [ bass-il-ix-im-ab ])
Drug Class: Interleukin inhibitors
Basiliximab Levels and Effects while Breastfeeding
Summary of Use during Lactation
No information is available on the clinical use of basiliximab during breastfeeding. Because basiliximab is a large protein molecule with a molecular weight of about 144,000 Da, the amount in milk is likely to be very low. It is also likely to be partially destroyed in the infant's gastrointestinal tract and absorption by the infant is probably minimal. Until more data become available, basiliximab should be used with caution during breastfeeding, especially while nursing a newborn or preterm infant. Waiting for at least 2 weeks postpartum to resume therapy may minimize transfer to the infant.[1] The manufacturer recommends that breastfeeding be discontinued during basiliximab therapy.
Drug Levels
Maternal Levels. Relevant published information was not found as of the revision date.
Infant Levels. Relevant published information was not found as of the revision date.
Effects in Breastfed Infants
Relevant published information was not found as of the revision date.
Effects on Lactation and Breastmilk
Relevant published information was not found as of the revision date.
References
- 1.
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Krysko KM, Dobson R, Alroughani R, et al. Family planning considerations in people with multiple sclerosis. Lancet Neurol. 2023;22:350–66. [PubMed: 36931808]
Substance Identification
Substance Name
Basiliximab
CAS Registry Number
179045-86-4
Drug Class
Breast Feeding
Lactation
Milk, Human
Antibodies, Monoclonal, Humanized
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- Drug Levels and Effects
- Substance Identification