Summary of Use during Lactation

No information is available on the clinical use of emicizumab during breastfeeding. Because emicizumab is a large protein molecule with a molecular weight of 145,600, the amount in milk is likely to be very low and absorption is unlikely because it is probably destroyed in the infant's gastrointestinal tract. Waiting for at least 2 weeks postpartum to resume therapy may minimize transfer to the infant.[1]

Drug Levels

Maternal Levels. Relevant published information was not found as of the revision date.

Infant Levels. Relevant published information was not found as of the revision date.

Effects in Breastfed Infants

Relevant published information was not found as of the revision date.

Effects on Lactation and Breastmilk

Relevant published information was not found as of the revision date.

References

1.

Krysko KM, Dobson R, Alroughani R, et al. Family planning considerations in people with multiple sclerosis. Lancet Neurol. 2023;22:350–66. [PubMed: 36931808]

Substance Name

Emicizumab

CAS Registry Number

1610943-06-0

Drug Class

Breast Feeding

Lactation

Milk, Human

Antibodies, Bispecific

Antibodies, Monoclonal, Humanized