Drug Detail:Fluvastatin (Fluvastatin [ floo-va-sta-tin ])
Drug Class: Statins
Fluvastatin Levels and Effects while Breastfeeding
Summary of Use during Lactation
No relevant published information exists on the use of fluvastatin during breastfeeding. Because of a concern with disruption of infant lipid metabolism, the consensus is that fluvastatin should not be used during breastfeeding. However, others have argued that children homozygous for familial hypercholesterolemia are treated with statins beginning at 1 year of age, that statins have low oral bioavailability, and risks to the breastfed infant are low, especially with rosuvastatin and pravastatin.[1] Until more data become available, an alternate drug may be preferred, especially while nursing a newborn or preterm infant.
Drug Levels
Maternal Levels. Relevant published information was not found as of the revision date.
Infant Levels. Relevant published information was not found as of the revision date.
Effects in Breastfed Infants
Relevant published information was not found as of the revision date.
Effects on Lactation and Breastmilk
Relevant published information was not found as of the revision date.
Alternate Drugs to Consider
Cholestyramine, Colesevelam, Colestipol
References
- 1.
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Holmsen ST, Bakkebo T, Seferowicz M et al. Statins and breastfeeding in familial hypercholesterolaemia. Tidsskr Nor Laegeforen. 2017;137:686-7. [PubMed: 28551957]
Substance Identification
Substance Name
Fluvastatin
CAS Registry Number
93957-54-1
Drug Class
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Breast Feeding
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Lactation
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Antilipemic Agents
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Anticholesteremic Agents
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Hydroxymethylglutaryl-CoA Reductase Inhibitors
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Disclaimer: Information presented in this database is not meant as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. The U.S. government does not warrant or assume any liability or responsibility for the accuracy or completeness of the information on this Site.
- Drug Levels and Effects
- Substance Identification