Note: This document contains side effect information about methohexital. Some dosage forms listed on this page may not apply to the brand name Brevital Sodium.
Applies to methohexital: injectable powder for injection, intravenous solution.
Warning
Avoid driving or operating machinery for 8 to 12 hours after you awake from anesthesia.
Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.
Tell your medical caregivers right away if you have:
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severe burning or swelling where the medicine was injected;
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fast heartbeats;
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a light-headed feeling, like you might pass out;
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muscle twitching; or
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confusion, anxiety, or restless feeling when coming out of anesthesia.
Common side effects may include:
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drowsiness;
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nausea, vomiting, stomach pain;
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chills or shivering;
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coughing, hiccups; or
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itching.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects.
For Healthcare Professionals
Applies to methohexital: injectable powder for injection, intravenous powder for injection, intravenous solution.
Cardiovascular
Frequency not reported: Circulatory depression, hypotension, tachycardia, peripheral vascular collapse, convulsions (associated with cardiorespiratory arrest)[Ref]
Respiratory
Frequency not reported: Respiratory depression (including apnea), cardiorespiratory arrest, laryngospasm, bronchospasm, hiccups, dyspnea, rhinitis[Ref]
Nervous system
Frequency not reported: Injury to nerves adjacent to injection site, seizure, headache[Ref]
Psychiatric
Frequency not reported: Emergence delirium, restlessness, and anxiety (especially in the presence of postoperative pain)[Ref]
Gastrointestinal
Frequency not reported: Nausea, vomiting, abdominal pain, salivation[Ref]
Hypersensitivity
Rare (less than 0.1%): Anaphylaxis[Ref]
Hepatic
Frequency not reported: Liver function tests abnormal[Ref]
Local
Frequency not reported: Injection site pain[Ref]
Hematologic
Frequency not reported: Thrombophlebitis[Ref]
Musculoskeletal
Frequency not reported: Skeletal muscle hyperactivity (twitching)[Ref]
Dermatologic
Frequency not reported: Erythema, pruritus, urticaria[Ref]
