Note: This document contains side effect information about doxazosin. Some dosage forms listed on this page may not apply to the brand name Cardura XL.
Summary
More frequent side effects include: dizziness. Continue reading for a comprehensive list of adverse effects.
Applies to doxazosin: oral tablets.
Side effects include:
Dizziness, headache, drowsiness, fatigue, edema, nausea, dyspnea, somnolence, abdominal pain, diarrhea.
For Healthcare Professionals
Applies to doxazosin: oral tablet, oral tablet extended release.
General
The most common adverse reaction was dizziness.[Ref]
Nervous system
Very common (10% or more): Dizziness (up to 19%)
Common (1% to 10%): Somnolence, headache, vertigo
Uncommon (0.1% to 1%): Cerebrovascular accident, hypoesthesia, syncope, tremor, tinnitus
Very rare (less than 0.01%): Dizziness postural, paresthesia
Frequency not reported: Taste disturbance[Ref]
Other
Very common (10% or more): Fatigue/malaise (12%)
Common (1% to 10%): Asthenia, chest pain, influenza-like symptoms
Uncommon (0.1% to 1%): Pain, facial edema[Ref]
Respiratory
Common (1% to 10%): Dyspnea, rhinitis, respiratory tract infection, bronchitis, cough
Uncommon (0.1% to 1%): Epistaxis
Very rare (less than 0.01%): Bronchospasm
Postmarketing reports: Bronchospasm aggravated[Ref]
Gastrointestinal
Common (1% to 10%): Dry mouth, abdominal pain, dyspepsia, nausea
Uncommon (0.1% to 1%): Constipation, flatulence, vomiting, gastroenteritis, diarrhea
Frequency not reported: Gastrointestinal obstruction[Ref]
Genitourinary
Common (1% to 10%): Polyuria, urinary tract infection, cystitis, urinary incontinence
Uncommon (0.1% to 1%): Dysuria, micturition frequency, hematuria, impotence
Very rare (less than 0.01%): Micturition disorder, nocturia, priapism
Frequency not reported: Retrograde ejaculation[Ref]
Cardiovascular
Common (1% to 10%): Hypotension, postural hypotension, palpitation, tachycardia
Uncommon (0.1% to 1%): Angina pectoris, myocardial infarction
Very rare (less than 0.01%): Bradycardia, cardiac arrhythmias, hot flushes[Ref]
Metabolic
Common (1% to 10%): Edema, peripheral edema
Uncommon (0.1% to 1%): Gout, appetite increased, anorexia, weight increased[Ref]
Musculoskeletal
Common (1% to 10%): Myalgia, back pain
Uncommon (0.1% to 1%): Arthralgia
Rare (less than 0.1%): Muscle cramps, muscle weakness[Ref]
Dermatologic
Common (1% to 10%): Pruritus
Uncommon (0.1% to 1%): Skin rash
Very rare (less than 0.01%): Urticaria, purpura, alopecia[Ref]
Psychiatric
Uncommon (0.1% to 1%): Agitation, depression, anxiety, insomnia, nervousness
Frequency not reported: Libido decreased[Ref]
Hepatic
Uncommon (0.1% to 1%): Abnormal liver function tests
Very rare (less than 0.01%): Cholestasis, hepatitis, jaundice
Postmarketing reports: Hepatitis cholestatic[Ref]
Immunologic
Uncommon (0.1% to 1%): Allergic drug reaction
Postmarketing reports: Allergic reaction[Ref]
Hematologic
Very rare (less than 0.01%): Leukopenia, thrombocytopenia
Frequency not reported: White blood cell counts decreased, neutrophil count decreased[Ref]
Ocular
Very rare (less than 0.01%): Blurred vision
Frequency not reported: Intraoperative Floppy Iris Syndrome (IFIS)[Ref]
Endocrine
Very rare (less than 0.01%): Gynecomastia[Ref]
Renal
Very rare (less than 0.01%): Diuresis increased[Ref]