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Home > Drugs > Alpha-adrenoreceptor antagonists > Cardura xl > Cardura xl Side Effects
Alpha-adrenoreceptor antagonists

Cardura XL Side Effects

Note: This document contains side effect information about doxazosin. Some dosage forms listed on this page may not apply to the brand name Cardura XL.

Summary

More frequent side effects include: dizziness. Continue reading for a comprehensive list of adverse effects.

Applies to doxazosin: oral tablets.

Side effects include:

Dizziness, headache, drowsiness, fatigue, edema, nausea, dyspnea, somnolence, abdominal pain, diarrhea.

For Healthcare Professionals

Applies to doxazosin: oral tablet, oral tablet extended release.

General

The most common adverse reaction was dizziness.[Ref]

Nervous system

Very common (10% or more): Dizziness (up to 19%)

Common (1% to 10%): Somnolence, headache, vertigo

Uncommon (0.1% to 1%): Cerebrovascular accident, hypoesthesia, syncope, tremor, tinnitus

Very rare (less than 0.01%): Dizziness postural, paresthesia

Frequency not reported: Taste disturbance[Ref]

Other

Very common (10% or more): Fatigue/malaise (12%)

Common (1% to 10%): Asthenia, chest pain, influenza-like symptoms

Uncommon (0.1% to 1%): Pain, facial edema[Ref]

Respiratory

Common (1% to 10%): Dyspnea, rhinitis, respiratory tract infection, bronchitis, cough

Uncommon (0.1% to 1%): Epistaxis

Very rare (less than 0.01%): Bronchospasm

Postmarketing reports: Bronchospasm aggravated[Ref]

Gastrointestinal

Common (1% to 10%): Dry mouth, abdominal pain, dyspepsia, nausea

Uncommon (0.1% to 1%): Constipation, flatulence, vomiting, gastroenteritis, diarrhea

Frequency not reported: Gastrointestinal obstruction[Ref]

Genitourinary

Common (1% to 10%): Polyuria, urinary tract infection, cystitis, urinary incontinence

Uncommon (0.1% to 1%): Dysuria, micturition frequency, hematuria, impotence

Very rare (less than 0.01%): Micturition disorder, nocturia, priapism

Frequency not reported: Retrograde ejaculation[Ref]

Cardiovascular

Common (1% to 10%): Hypotension, postural hypotension, palpitation, tachycardia

Uncommon (0.1% to 1%): Angina pectoris, myocardial infarction

Very rare (less than 0.01%): Bradycardia, cardiac arrhythmias, hot flushes[Ref]

Metabolic

Common (1% to 10%): Edema, peripheral edema

Uncommon (0.1% to 1%): Gout, appetite increased, anorexia, weight increased[Ref]

Musculoskeletal

Common (1% to 10%): Myalgia, back pain

Uncommon (0.1% to 1%): Arthralgia

Rare (less than 0.1%): Muscle cramps, muscle weakness[Ref]

Dermatologic

Common (1% to 10%): Pruritus

Uncommon (0.1% to 1%): Skin rash

Very rare (less than 0.01%): Urticaria, purpura, alopecia[Ref]

Psychiatric

Uncommon (0.1% to 1%): Agitation, depression, anxiety, insomnia, nervousness

Frequency not reported: Libido decreased[Ref]

Hepatic

Uncommon (0.1% to 1%): Abnormal liver function tests

Very rare (less than 0.01%): Cholestasis, hepatitis, jaundice

Postmarketing reports: Hepatitis cholestatic[Ref]

Immunologic

Uncommon (0.1% to 1%): Allergic drug reaction

Postmarketing reports: Allergic reaction[Ref]

Hematologic

Very rare (less than 0.01%): Leukopenia, thrombocytopenia

Frequency not reported: White blood cell counts decreased, neutrophil count decreased[Ref]

Ocular

Very rare (less than 0.01%): Blurred vision

Frequency not reported: Intraoperative Floppy Iris Syndrome (IFIS)[Ref]

Endocrine

Very rare (less than 0.01%): Gynecomastia[Ref]

Renal

Very rare (less than 0.01%): Diuresis increased[Ref]

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