Applies to chlorpheniramine / dextromethorphan / pseudoephedrine: oral liquid.
Serious side effects
WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Tell your doctor or get medical help right away if you have any of the following signs or symptoms that may be related to a very bad side effect:
- Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing, swallowing, or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat.
Other side effects
All drugs may cause side effects. However, many people have no side effects or only have minor side effects. Call your doctor or get medical help if any of these side effects or any other side effects bother you or do not go away:
- Dizziness.
- Feeling nervous and excitable.
- Not able to sleep.
- Feeling sleepy.
These are not all of the side effects that may occur. If you have questions about side effects, call your doctor. Call your doctor for medical advice about side effects.
You may report side effects to the FDA at 1-800-332-1088. You may also report side effects at https://www.fda.gov/medwatch.
For Healthcare Professionals
Applies to chlorpheniramine/dextromethorphan/pseudoephedrine: oral liquid, oral suspension extended release, oral tablet chewable.
Nervous system
Frequency not reported: Excitability, drowsiness, nervousness, sleeplessness (combination product); headache, tremor, dizziness, insomnia (pseudoephedrine); sedation, impaired mental status (chlorpheniramine)[Ref]
Cardiovascular
Frequency not reported: Elevated blood pressure, tachycardia (pseudoephedrine)[Ref]
Genitourinary
Frequency not reported: Urinary retention (pseudoephedrine)[Ref]
Ocular
Frequency not reported: Elevated intraocular pressure (pseudoephedrine)[Ref]
Other
Frequency not reported: Fatigue (chlorpheniramine)[Ref]
