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Home > Drugs > Upper respiratory combinations > Codeine, phenylephrine, and triprolidine > Codeine, phenylephrine, and triprolidine Side Effects
Upper respiratory combinations

Codeine / phenylephrine / triprolidine Side Effects

Applies to codeine / phenylephrine / triprolidine: oral liquid.

Warning

Codeine can slow or stop your breathing, and may be habit-forming. MISUSE OF THIS MEDICINE CAN CAUSE ADDICTION, OVERDOSE, OR DEATH, especially in a child or other person using the medicine without a prescription.

This medicine is not for use in anyone under 18.

You should not use antihistamine medication to make a child sleepy.

Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Like other narcotic medications, codeine can slow your breathing. Death may occur if breathing becomes too weak.

A person caring for you should seek emergency medical attention if you have slow breathing with long pauses, blue colored lips, or if you are hard to wake up.

Like other narcotic medications, codeine can slow your breathing. Death may occur if breathing becomes too weak.

Stop taking this medicine and call your doctor at once if you have:

  • noisy breathing, sighing, shallow breathing;

  • a slow heart rate or weak pulse;

  • nervousness, trouble sleeping;

  • severe headache or dizziness, ringing in your ears;

  • severe constipation; or

  • little or no urination.

Serious side effects may be more likely in older adults and those who are overweight, malnourished, or debilitated.

Common side effects may include:

  • dizziness, drowsiness, tired feeling;

  • dry mouth, nose, or throat;

  • blurred vision;

  • nausea, vomiting, constipation; or

  • sleep problems (insomnia).

Side effects such as dry mouth, constipation, and confusion may be more likely in older adults.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects.

For Healthcare Professionals

Applies to codeine/phenylephrine/triprolidine: oral liquid.

General

The most commonly occurring side effects include dry mouth, dizziness, sleepiness, and disturbed coordination.[Ref]

Cardiovascular

Frequency not reported: Hypotension, palpitations, tachycardia, extrasystoles

Gastrointestinal

Frequency not reported: Dry mouth, dry throat, epigastric distress, anorexia, nausea, vomiting, diarrhea, constipation

Genitourinary

Frequency not reported: Urinary frequency, difficult urination, urinary retention

Psychiatric

Frequency not reported: Confusion, restlessness, excitation, anxiety, nervousness, irritability, insomnia, euphoria, hysteria, hallucination

Ocular

Frequency not reported: Blurred vision, diplopia

Other

Frequency not reported: Chills, fatigue, vertigo, tinnitus

Dermatologic

Frequency not reported: Drug rash, photosensitivity, excessive perspiration, urticaria

Nervous system

Frequency not reported: Sedation, sleepiness, dizziness, disturbed coordination, tremor, paresthesias, neuritis, convulsions, CNS depression

Respiratory

Frequency not reported: Nasal dryness, thickening of bronchial secretions, tightness of chest and wheezing, nasal stuffiness, respiratory depression

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