Drug Class: Upper respiratory combinations
Usual Adult Dose for Cold Symptoms
Acetaminophen/chlorpheniramine/dextromethorphan 500 mg-2 mg-15 mg tablets: 2 tablets orally every 6 hours, while symptoms persist, not to exceed 8 tablets in 24 hours, or as directed by a doctor.
Usual Adult Dose for Influenza
Acetaminophen/chlorpheniramine/dextromethorphan 500 mg-2 mg-15 mg tablets: 2 tablets orally every 6 hours, while symptoms persist, not to exceed 8 tablets in 24 hours, or as directed by a doctor.
Usual Pediatric Dose for Cold Symptoms
Acetaminophen/chlorpheniramine/dextromethorphan 160 mg-1 mg-5 mg/5 mL oral suspension:
Greater than or equal to 6 years to less than 12 years: 10 mL orally every 4 hours not to exceed 5 doses daily.
Acetaminophen/chlorpheniramine/dextromethorphan 160 mg-1 mg-7.5 mg/5 mL oral liquid:
Greater than or equal to 6 years to less than 12 years: 10 mL orally every 6 hours not to exceed 4 doses daily.
Acetaminophen/chlorpheniramine/dextromethorphan 500 mg-2 mg-15 mg tablets:
Greater than or equal to 12 years: 2 tablets orally every 6 hours, while symptoms persist, not to exceed 8 tablets in 24 hours, or as directed by a doctor.
Usual Pediatric Dose for Influenza
Acetaminophen/chlorpheniramine/dextromethorphan 160 mg-1 mg-5 mg/5 mL oral suspension:
Greater than or equal to 6 years to less than 12 years: 10 mL orally every 4 hours not to exceed 5 doses daily.
Acetaminophen/chlorpheniramine/dextromethorphan 160 mg-1 mg-7.5 mg/5 mL oral liquid:
Greater than or equal to 6 years to less than 12 years: 10 mL orally every 6 hours not to exceed 4 doses daily.
Acetaminophen/chlorpheniramine/dextromethorphan 500 mg-2 mg-15 mg tablets:
Greater than or equal to 12 years: 2 tablets orally every 6 hours, while symptoms persist, not to exceed 8 tablets in 24 hours, or as directed by a doctor.
Renal Dose Adjustments
Data not available
Liver Dose Adjustments
Data not available
Precautions
Use with caution in patients with liver disease. Chronic use of acetaminophen is not recommended in patients with liver disease.
The elimination of chlorpheniramine may be prolonged in patients with renal dysfunction. These patients should be monitored for excessive sedation and other adverse effects that may result from chlorpheniramine accumulation.
Dialysis
Data not available