Usual Adult Dose for Intraocular Hypertension

0.25% suspension: One drop in the affected eye(s) twice a day
0.5% solution: One to two drops in the affected eye(s) twice a day

Comments:

• In some patients, the intraocular pressure lowering responses may require a few weeks to stabilize.
• If the intraocular pressure is not adequately controlled on this regimen, concomitant therapy with pilocarpine and other miotics, and/or epinephrine and/or carbonic anhydrase inhibitors may be instituted.

Use: To lower intraocular pressure in patients with chronic open-angle glaucoma and intraocular hypertension

Usual Adult Dose for Glaucoma (Open Angle)

0.25% suspension: One drop in the affected eye(s) twice a day
0.5% solution: One to two drops in the affected eye(s) twice a day

Comments:

• In some patients, the intraocular pressure lowering responses may require a few weeks to stabilize.
• If the intraocular pressure is not adequately controlled on this regimen, concomitant therapy with pilocarpine and other miotics, and/or epinephrine and/or carbonic anhydrase inhibitors may be instituted.

Use: To lower intraocular pressure in patients with chronic open-angle glaucoma and intraocular hypertension

Usual Pediatric Dose for Intraocular Hypertension

0.25% suspension: One drop in the affected eye(s) twice a day

Comments:

• In some patients, the intraocular pressure lowering responses may require a few weeks to stabilize.

If the intraocular pressure of the patient is not adequately controlled on this regimen, concomitant therapy with pilocarpine and other miotics, and/or epinephrine and/or carbonic anhydrase inhibitors may be instituted.

Use: To lower intraocular pressure in patients with chronic open-angle glaucoma and intraocular hypertension

Usual Pediatric Dose for Glaucoma (Open Angle)

0.25% suspension: One drop in the affected eye(s) twice a day

Comments:

• In some patients, the intraocular pressure lowering responses may require a few weeks to stabilize.

If the intraocular pressure of the patient is not adequately controlled on this regimen, concomitant therapy with pilocarpine and other miotics, and/or epinephrine and/or carbonic anhydrase inhibitors may be instituted.

Use: To lower intraocular pressure in patients with chronic open-angle glaucoma and intraocular hypertension

Renal Dose Adjustments

Data not available

Liver Dose Adjustments

Data not available

Precautions

0.5% solution: Safety and efficacy have not been established in patients younger than 18 years.

Consult WARNINGS section for additional precautions.

Dialysis

Data not available

Other Comments

Storage requirements:

• Protect from light
• Store product in the original outer carton.
• The product should be discarded one month after opening.

Patient advice:

• The bottle should be shaken well prior to each use.
• Patients should also be advised that if they develop any intercurrent ocular condition (e.g., trauma, ocular surgery, or infection), they should immediately seek their physician's advice concerning the continued use of this drug.
• When using nasolacrimal occlusion or closing the eyelids for 2 minutes, the systemic absorption is reduced.
• Do not touch dropper tip to any surface.