Drug Detail:Clarinex-d 24 hour (Desloratadine and pseudoephedrine [ des-loe-rat-a-deen-and-soo-doe-ee-fed-rin ])
Drug Class: Upper respiratory combinations
Usual Adult Dose for Allergic Rhinitis
2.5 mg desloratadine / 120 mg pseudoephedrine tablets: 1 tablet orally every 12 hours
Maximum dose: 1 tablet twice daily
Comments:
- Higher doses or more frequent dosing has not shown increased effectiveness, but may have more adverse effects.
Use: Relief of seasonal allergic rhinitis symptoms
Usual Pediatric Dose for Allergic Rhinitis
12 and older:
2.5 mg desloratadine / 120 mg pseudoephedrine tablets: 1 tablet orally every 12 hours
Maximum dose: 1 tablet twice daily
Comments:
- Higher doses or more frequent dosing has not shown increased effectiveness, but may have more adverse effects.
Use: Relief of seasonal allergic rhinitis symptoms
Renal Dose Adjustments
Not recommended.
- Renally impaired patients may accumulate pseudoephedrine.
Liver Dose Adjustments
Not recommended.
Precautions
CONTRAINDICATIONS:
- Hypersensitivity to any of the ingredients
- Narrow angle glaucoma
- Urinary retention
- Current monoamine oxidase inhibitor (MAOI) use or use within 14 days of stopping a MAOI
- Severe hypertension
- Severe coronary artery disease
Safety and efficacy have not been established in patients younger than 12 years.
Consult WARNINGS section for additional precautions.
Dialysis
Data not available
- Use should be avoided in renal impairment.
- Renally impaired patients may accumulate pseudoephedrine.
Other Comments
Administration advice:
- Swallow extended release tablets whole; do not crush, break, or chew.
- Do not exceed the recommended dosage.
- May be taken with or without food.