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Home > Drugs > Aromatase inhibitors > Exemestane > Exemestane Dosage
Aromatase inhibitors
https://themeditary.com/dosage-information/exemestane-dosage-405.html

Exemestane Dosage

Drug Detail:Exemestane (Exemestane)

Drug Class: Aromatase inhibitors Hormones / antineoplastics

Contents
Uses Warnings Before Taking Dosage Side effects Interactions

Usual Adult Dose for Breast Cancer

25 mg orally once a day

Comment:

  • This drug is not indicated for the treatment of breast cancer in premenopausal women.

Uses:
  • Adjuvant treatment of postmenopausal women with estrogen-receptor positive early breast cancer who have received two to three years of tamoxifen and are switched to exemestane for completion of a total of five consecutive years of adjuvant hormonal therapy.
  • Treatment of advanced breast cancer in postmenopausal women whose disease has progressed following tamoxifen therapy.

Renal Dose Adjustments

No adjustment recommended

Liver Dose Adjustments

No adjustment recommended

Dose Adjustments

Patients taking exemestane with a potent CYP450 3A4 inducer such as rifampin or phenytoin: 50 mg once a day after a meal

Precautions

CONTRAINDICATIONS:

  • Hypersensitivity to the active component or any of the ingredients

Safety and efficacy have not been established in patients younger than 18 years.

Consult WARNINGS section for additional precautions.

Dialysis

Data not available

Other Comments

Administration Advice:

  • This drug should be taken after a meal.

Monitoring:
  • Bone mineral density (BMD) in women with or at risk of developing osteoporosis

Patient advice:
  • Exemestane may cause dizziness, asthenia, and somnolence. Patients should avoid driving or operating machinery if they experience these adverse effects.
  • Advise females of reproductive potential of the potential risk to a fetus and to use effective contraception during therapy and for at least 1 month after the last dose.
  • Advise females to contact their healthcare provider if they become pregnant, or if pregnancy is suspected, during treatment.
  • Advise women not to breastfeed during treatment and for at least 1 month after the last dose.

Frequently asked questions

  • Which is better - Aromasin or Femara?
  • Aromasin vs Femara - how do they compare?
  • How long do you need to take Aromasin?
  • Should you take Aromasin with food?
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