2.1 Important Dosage and Administration Instructions

​Use the lowest effective dosage for the shortest duration consistent with individual patient treatment goals [see Warnings and Precautions (5)].

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​Initiate the dosing regimen for each patient individually, taking into account the patient's severity of pain, patient response, prior analgesic treatment experience, and risk factors for addiction, abuse, and misuse [see Warnings and Precautions (5.1)].

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2.2 Dosing Information

​One or two capsules every 4 hours. Total daily dosage should not exceed 6 capsules.

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2.3 Discontinuation of FIORINAL with CODEINE

​While not indicated for around-the-clock therapy, when a patient who has been taking FIORINAL with CODEINE regularly and may be physically dependent no longer requires therapy with FIORINAL with CODEINE, taper the dose gradually, by 25% to 50% every 2 to 4 days, while monitoring carefully for signs and symptoms of withdrawal. If the patient develops these signs or symptoms, raise the dose to the previous level and taper more slowly, either by increasing the interval between decreases, decreasing the amount of change in dose, or both. Do not abruptly discontinue FIORINAL with CODEINE in a physically-dependent patient [see Warnings and Precautions (5.14), Drug Abuse and Dependence (9.3)].