Drug Detail:Good sense allergy relief (fluticasone) (Fluticasone nasal [ floo-tik-a-sone ])
Drug Class: Nasal steroids
Usual Adult Dose for Rhinitis
Fluticasone furoate: 2 sprays (27.5 mcg/spray) in each nostril once a day
Fluticasone propionate: 1 or 2 sprays (50 mcg/spray) in each nostril once a day as needed
Comments:
Fluticasone furoate:
- When maximum benefit has been achieved and symptoms have been controlled, reducing the dosage to 55 mcg (1 spray in each nostril) once a day may be effective.
Use: Treatment of symptoms of seasonal and perennial allergic rhinitis
Usual Pediatric Dose for Rhinitis
2 to 11 years:
Fluticasone furoate: 1 spray (27.5 mcg/spray) in each nostril once a day
4 to 11 years:
Fluticasone propionate: 1 spray (50 mcg/spray) in each nostril once a day
12 years or older:
Fluticasone furoate: 2 sprays (27.5 mcg/spray) in each nostril once a day
Fluticasone propionate: 1 or 2 sprays (50 mcg/spray) in each nostril once a day as needed
Comments:
Fluticasone furoate:
- Children between 2 to 11 years not adequately responding to 55 mcg may use 110 mcg (2 sprays in each nostril) once a day.
- When maximum benefit has been achieved and symptoms have been controlled, reducing the dosage to 55 mcg (1 spray in each nostril) once a day may be effective.
Use: Treatment of symptoms of seasonal and perennial allergic rhinitis
Renal Dose Adjustments
No adjustment recommended
Liver Dose Adjustments
Moderate or severe hepatic impairment: Use with caution
Precautions
Safety and efficacy have not been established in patients younger than 2 years.
Consult WARNINGS section for additional precautions.
Dialysis
Data not available
Other Comments
Administration advice:
- This drug should be administered by the intranasal route only.
- The nasal spray should be primed before using for the first time by shaking the contents well and releasing 6 sprays into the air away from the face.
- When the nasal spray has not been used for more than 30 days or if the cap has been left off the bottle for 5 days or longer, the pump should be primed again until a fine mist appears.
- The nasal spray should be shaken well before each use.
Storage requirements:
- The nasal device should be stored in the upright position with the cap in place between 15 and 30 C.
- Do not freeze or refrigerate.
Monitoring:
- Endocrine: HPA-axis suppression (Urinary free-cortisol test, ACTH-stimulation test)
