Usual Adult Dose for Cough and Nasal Congestion

Immediate release tablets: 1 tablet orally every 4 hours
Maximum dose: 4 tablets per 24 hours

Extended release (600 mg/ 60 mg) tablets: 2 tablets orally every 12 hours
Maximum dose: 4 tablets per 24 hours

Maximum strength (1200 mg/ 120 mg) extended release tablets: 1 tablet orally every 12 hours
Maximum dose: 2 tablets per 24 hours

Usual Pediatric Dose for Cough and Nasal Congestion

Immediate release tablets:
12 years and older: 1 tablet orally every 4 hours
Maximum dose: 4 tablets per 24 hours

6 to 12 years: One half tablet orally every 4 hours
Maximum dose: 2 tablets per 24 hours

Extended release (600 mg/ 60 mg) tablets:
12 years and older: 2 tablets orally every 12 hours
Maximum dose: 4 tablets per 24 hours

Maximum strength (1200 mg/ 120 mg) extended release tablets:
12 years and older: 1 tablet orally every 12 hours
Maximum dose: 2 tablets per 24 hours

25 mg/ 7.5 mg/ mL liquid:
2 to under 6 years (11 to 21 kg): 2 mL every 4 to 6 hours
Maximum dose: 4 doses per 24 hours

Renal Dose Adjustments

Data not available

Liver Dose Adjustments

Data not available

Precautions

CONTRAINDICATIONS:

• Current use of a monoamine oxidase inhibitor (MAOI) or use within 14 days of stopping a MAOI

Dialysis

Data not available

Other Comments

Administration advice:

• Do not crush, break, or chew extended or sustained release tablets.
• Extended release tablets may be taken without regard for timing of meals