Miscellaneous anxiolytics, sedatives and hypnotics
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Quviviq Dosage

Drug Detail:Quviviq (Daridorexant)

Generic Name: daridorexant 25mg

Dosage Form: tablet, film coated

Drug Class: Miscellaneous anxiolytics, sedatives and hypnotics

Contents
Uses Warnings Before Taking Dosage Side effects Interactions

Recommended Dosage

The recommended dosage range is 25 mg to 50 mg of QUVIVIQ taken orally no more than once per night within 30 minutes of going to bed (with at least 7 hours remaining prior to planned awakening).

Time to sleep onset may be delayed if taken with or soon after a meal [see Clinical Pharmacology (12.3)].

Dosage Recommendations for Concomitant Use with CYP3A4 Inhibitors or CYP3A4 Inducers

Co-administration with Strong CYP3A4 Inhibitors

Avoid concomitant use of QUVIVIQ with strong inhibitors of CYP3A4 [see Drug Interactions (7.1), Clinical Pharmacology (12.3)].

Co-administration with Moderate CYP3A4 Inhibitors

The recommended dosage of QUVIVIQ is 25 mg no more than once per night when used with moderate inhibitors of CYP3A4 [see Drug Interactions (7.1), Clinical Pharmacology (12.3)].

Co-administration with Strong or Moderate CYP3A4 Inducers

Avoid concomitant use of QUVIVIQ with strong or moderate CYP3A4 inducers [see Drug Interactions (7.1)].

Dosage Recommendations for Patients with Hepatic Impairment

The maximum recommended dosage in patients with moderate hepatic impairment (Child-Pugh score 7–9) is 25 mg of QUVIVIQ no more than once per night [see Use in Specific Populations (8.6), Clinical Pharmacology (12.3)].

QUVIVIQ is not recommended in patients with severe hepatic impairment (Child-Pugh score ≥ 10) [see Use in Specific Populations (8.6)].

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