Usual Adult Dose for Chronic Obstructive Pulmonary Disease - Maintenance
One 175 mcg vial once a day via a nebulizer with a mouthpiece
Renal Dose Adjustments
No adjustment recommended.
Monitor severe renal impairment patients for systemic antimuscarinic adverse effects.
Liver Dose Adjustments
Not recommended with any degree of hepatic impairment.
In moderate hepatic impairment, systemic exposure to the drug is unchanged, but exposure to the active metabolite is increased.
Safety has not been evaluated in COPD patients with any level of hepatic impairment.
Precautions
CONTRAINDICATIONS:
Hypersensitivity to any of the ingredients
Safety and efficacy have not been established in patients younger than 18 years.
Consult WARNINGS section for additional precautions.
Dialysis
Data not available
Other Comments
Administration advice:
For inhalation via a standard jet nebulizer connected to an air compressor; safety and efficacy have not been established with non-compressor based nebulizer systems.
Safety and efficacy have been established with the PARLIC(R) Sprint nebulizer with mouthpiece and the PARI Trek(R) compressor.
Only remove the unit dose vial from the pouch immediately before administration.
Storage requirements:
Store in protective foil pouch.
Store at room temperature; protect from direct sunlight and excessive heat
