Renin inhibitors
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Tekturna Dosage

Drug Detail:Tekturna (Aliskiren [ a-lis-ke-rin ])

Generic Name: ALISKIREN HEMIFUMARATE 150mg

Dosage Form: tablet, film coated

Drug Class: Renin inhibitors

Contents
Uses Warnings Before Taking Dosage Side effects Interactions

Recommended Dosage

In adult patients and in pediatric patients weighing 50 kg or greater who are at least 6 years of age, the recommended starting dose of Tekturna is 150 mg once daily. In patients whose blood pressure is not adequately controlled, the daily dose may be increased to 300 mg once daily. Doses above 300 mg did not give an increased blood pressure response but resulted in an increased rate of diarrhea. The antihypertensive effect of a given dosage is substantially attained (85% to 90%) by 2 weeks.

Relationship to Meals

Patients should establish a routine pattern for taking Tekturna with regard to meals. High-fat meals decrease absorption substantially [see Clinical Pharmacology ( 12.3)].

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