Applies to erythromycin topical: topical gel/jelly, topical pad, topical powder, topical solution.
Serious side effects
Along with its needed effects, erythromycin topical may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Other side effects
Some side effects of erythromycin topical may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.
Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:
For erythromycin ointment
Less common
- Peeling
- redness
For erythromycin pledget (swab), topical gel, or topical liquid form
More common
- Dry or scaly skin
- irritation
- itching
- stinging or burning feeling
Less common
- Peeling
- redness
For Healthcare Professionals
Applies to erythromycin topical: topical gel, topical ointment, topical solution, topical swab.
General
The most commonly reported side effects included burning, dryness, erythema, itching, and peeling.[Ref]
Local
Very common (10% or more): Burning/burning sensation (up to 25%)
Uncommon (0.1% to 1%): Desquamation, dryness, erythema, itching, oiliness, peeling[Ref]
Dermatologic
Frequency not reported: Mild to severe skin irritation, skin tenderness[Ref]
Hypersensitivity
Frequency not reported: Generalized urticarial reaction[Ref]
Generalized urticarial reactions required systemic steroid treatment.[Ref]
Ocular
Frequency not reported: Eye irritation[Ref]
