Note: This document contains side effect information about plasma protein fraction. Some dosage forms listed on this page may not apply to the brand name Octaplas.

Applies to plasma protein fraction: parenteral solution for injection.

Side effects include:

Flushing, urticaria, nausea, headache, back pain.

For Healthcare Professionals

Applies to plasma protein fraction: intravenous solution.

Cardiovascular

Very rare (less than 0.01%): Cardiac arrest, arrhythmia, tachycardia, thromboembolism, hypotension, hypertension, circulatory overload, circulatory collapse, flushing

Frequency not reported: Severe hypotension, chest pain, chest discomfort^[Ref]

Dermatologic

Common (1% to 10%): Urticaria, pruritus

Very rare (less than 0.01%): Rash (erythematous), hyperhidrosis^[Ref]

Gastrointestinal

Uncommon (0.1% to 1%): Nausea, vomiting

Very rare (less than 0.01%): Abdominal pain^[Ref]

Musculoskeletal

Very rare (less than 0.01%): Back pain^[Ref]

Nervous system

Uncommon (0.1% to 1%): Hypoesthesia

Very rare (less than 0.01%): Dizziness, paresthesia

Frequency not reported: Headache^[Ref]

Hematologic

Very rare (less than 0.01%): Hemolytic anemia, hemorrhagic diathesis, citrate toxicity

Frequency not reported: Hyperfibrinolysis^[Ref]

Hypersensitivity

Uncommon (0.1% to 1%): Anaphylaxis

Rare (less than 0.1%): Hypersensitivity^[Ref]

Local

Very rare (less than 0.01%): Application site reaction^[Ref]

Metabolic

Frequency not reported: Alkalosis^[Ref]

Psychiatric

Very rare (less than 0.01%): Anxiety, agitation, restlessness^[Ref]

Respiratory

Uncommon (0.1% to 1%): Hypoxia

Very rare (less than 0.01%): Respiratory failure, pulmonary hemorrhage, bronchospasm, pulmonary edema, dyspnea, respiratory disorder, oxygen saturation decreased

Frequency not reported: Tachypnea^[Ref]

Other

Uncommon (0.1% to 1%): Pyrexia

Very rare (less than 0.01%): Chills, localized edema, malaise, antibody test positive^[Ref]