Applies to pancuronium: parenteral injection.
Warning
- Should be administered only by adequately trained clinicians experienced in the use and complications of neuromuscular blocking agents.100
Side effects include:
Various degrees of skeletal muscle weakness.
For Healthcare Professionals
Applies to pancuronium: intravenous solution.
Hypersensitivity
Uncommon (0.1% to 1%): Severe anaphylactic reactions[Ref]
Local
Uncommon (0.1% to 1%): Pain and burning at injection site[Ref]
Musculoskeletal
Frequency not reported: Prolonged paralysis, disuse atrophy, and areflexia have been reported with prolonged use of this drug[Ref]
Ocular
Frequency not reported: Decreased intraocular pressure, miosis[Ref]
Respiratory
Rare (less than 0.1%): Bronchospasm, wheezing
Frequency not reported: Apnea, respiratory depression[Ref]
Cardiovascular
Very common (10% or more): Mild to moderate increase in blood pressure and/or pulse rate (10%)
Rare (less than 0.1%): Hypotension, cardiovascular collapse, flushing, edema, arrhythmia, bradycardia
Frequency not reported: Dysrhythmias, increased cardiac output[Ref]
Dermatologic
Uncommon (0.1% to 1%): Transient rash, pruritus, redness[Ref]
Gastrointestinal
Frequency not reported: Hypersalivation[Ref]