Uses of Glipizide Extended-Release Tablets:

• It is used to lower blood sugar in patients with high blood sugar (diabetes).

What do I need to tell my doctor BEFORE I take Glipizide Extended-Release Tablets?

• If you have an allergy to glipizide or any other part of this medicine (glipizide extended-release tablets).
• If you have a sulfa allergy.
• If you are allergic to this medicine (glipizide extended-release tablets); any part of this medicine (glipizide extended-release tablets); or any other drugs, foods, or substances. Tell your doctor about the allergy and what signs you had.
• If you have any of these health problems: Acidic blood problem or type 1 diabetes.
• If you have G6PD deficiency.
• If you have a narrowing of the GI (gastrointestinal) tract or a bowel block.

This is not a list of all drugs or health problems that interact with this medicine (glipizide extended-release tablets).

Tell your doctor and pharmacist about all of your drugs (prescription or OTC, natural products, vitamins) and health problems. You must check to make sure that it is safe for you to take this medicine (glipizide extended-release tablets) with all of your drugs and health problems. Do not start, stop, or change the dose of any drug without checking with your doctor.

What are some things I need to know or do while I take Glipizide Extended-Release Tablets?

• Tell all of your health care providers that you take this medicine (glipizide extended-release tablets). This includes your doctors, nurses, pharmacists, and dentists.
• Avoid driving and doing other tasks or actions that call for you to be alert until you see how this medicine (glipizide extended-release tablets) affects you.
• Check your blood sugar as you have been told by your doctor.
• Have blood work checked as you have been told by the doctor. Talk with the doctor.
• This medicine may affect certain lab tests. Tell all of your health care providers and lab workers that you take this medicine (glipizide extended-release tablets).
• Follow the diet and workout plan that your doctor told you about.
• Do not drive if your blood sugar has been low. There is a greater chance of you having a crash.
• Avoid drinking alcohol while taking this medicine (glipizide extended-release tablets).
• If you also take colesevelam, take it at least 4 hours after you take this medicine (glipizide extended-release tablets).
• It may be harder to control blood sugar during times of stress such as fever, infection, injury, or surgery. A change in physical activity, exercise, or diet may also affect blood sugar.
• This medicine may raise the chance of death from heart disease. Talk with your doctor.
• Low blood sugar may happen with this medicine (glipizide extended-release tablets). Very low blood sugar can lead to seizures, passing out, long lasting brain damage, and sometimes death. Talk with the doctor.
• If you are 65 or older, use this medicine (glipizide extended-release tablets) with care. You could have more side effects.
• You may see the tablet shell in your stool. This is normal and not a cause for concern.
• Tell your doctor if you are pregnant or plan on getting pregnant. You will need to talk about the benefits and risks of using this medicine (glipizide extended-release tablets) while you are pregnant.
• Low blood sugar has happened in infants born to women who took a drug like this one until the birth date. If this medicine (glipizide extended-release tablets) is used during pregnancy, you will need to stop taking it some time before your due date. Talk with your doctor.
• Tell your doctor if you are breast-feeding. You will need to talk about any risks to your baby.

How is this medicine (Glipizide Extended-Release Tablets) best taken?

Use this medicine (glipizide extended-release tablets) as ordered by your doctor. Read all information given to you. Follow all instructions closely.

• Take with the first meal of the day.
• Swallow whole. Do not chew, break, or crush.
• Be sure you know what to do if you do not eat as much as normal or if you skip a meal.

What do I do if I miss a dose?

• Take a missed dose as soon as you think about it.
• If it is close to the time for your next dose, skip the missed dose and go back to your normal time.
• Do not take 2 doses at the same time or extra doses.

What are some side effects that I need to call my doctor about right away?

WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Tell your doctor or get medical help right away if you have any of the following signs or symptoms that may be related to a very bad side effect:

• Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing, swallowing, or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat.
• Change in eyesight.
• Slurred speech.
• Tingling.
• Feeling very tired or weak.
• Low blood sugar can happen. The chance may be raised when this medicine (glipizide extended-release tablets) is used with other drugs for diabetes. Signs may be dizziness, headache, feeling sleepy or weak, shaking, fast heartbeat, confusion, hunger, or sweating. Call your doctor right away if you have any of these signs. Follow what you have been told to do for low blood sugar. This may include taking glucose tablets, liquid glucose, or some fruit juices.

What are some other side effects of Glipizide Extended-Release Tablets?

All drugs may cause side effects. However, many people have no side effects or only have minor side effects. Call your doctor or get medical help if any of these side effects or any other side effects bother you or do not go away:

• Dizziness.
• Diarrhea.
• Feeling nervous and excitable.
• Gas.

These are not all of the side effects that may occur. If you have questions about side effects, call your doctor. Call your doctor for medical advice about side effects.

You may report side effects to the FDA at 1-800-332-1088. You may also report side effects at https://www.fda.gov/medwatch.

If OVERDOSE is suspected:

If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.

How do I store and/or throw out Glipizide Extended-Release Tablets?

• Store at room temperature.
• Store in a dry place. Do not store in a bathroom.
• Store in original container.
• Keep all drugs in a safe place. Keep all drugs out of the reach of children and pets.
• Throw away unused or expired drugs. Do not flush down a toilet or pour down a drain unless you are told to do so. Check with your pharmacist if you have questions about the best way to throw out drugs. There may be drug take-back programs in your area.

Consumer Information Use and Disclaimer

• If your symptoms or health problems do not get better or if they become worse, call your doctor.
• Do not share your drugs with others and do not take anyone else's drugs.
• Some drugs may have another patient information leaflet. Check with your pharmacist. If you have any questions about this medicine (glipizide extended-release tablets), please talk with your doctor, nurse, pharmacist, or other health care provider.
• If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.