Note: This document contains side effect information about atogepant. Some dosage forms listed on this page may not apply to the brand name Qulipta.

Applies to atogepant: oral tablets.

Side effects include:

Common adverse reactions (≥4%) include nausea, constipation, and fatigue.

For Healthcare Professionals

Applies to atogepant: oral tablet.

General

The more commonly reported adverse reactions have included nausea, constipation, and fatigue.^[Ref]

Gastrointestinal

Common (1% to 10%): Nausea, constipation

Metabolic

Common (1% to 10%): Decreased appetite, weight loss

Weight loss of greater than 7% of body weight was reported for 3.8% of patients receiving 10 mg/day, 3.2% for 30 mg/day, and 4.9% for patients receiving 60 mg/day (compared to 2.8% for placebo).

Hepatic

Transaminase elevations greater than 3 times the upper limit of normal (3 x ULN) were reported similarly for patients receiving this drug and those receiving placebo (1% vs 1.8%). Temporally associated cases of transaminase elevations were reported with use of this drug; they were asymptomatic and resolved within 8 weeks of discontinuation.^[Ref]

Common (1% to 10%): Liver enzyme elevations^[Ref]

Nervous system

Common (1% to 10%): Fatigue/somnolence