Note: This document contains side effect information about methsuximide. Some dosage forms listed on this page may not apply to the brand name Celontin.
Applies to methsuximide: oral capsule.
Serious side effects of Celontin
Along with its needed effects, methsuximide (the active ingredient contained in Celontin) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor immediately if any of the following side effects occur while taking methsuximide:
Rare
- Attempts at killing oneself
- feeling that others are watching you or controlling your behavior
- feeling that others can hear your thoughts
- feeling, seeing, or hearing things that are not there
- severe mood or mental changes
- unusual behavior
Incidence not known
- Attack, assault, or force
- blistering, peeling, or loosening of the skin
- blood in the urine
- bloody, black, or tarry stools
- chest pain
- chills
- cloudy urine
- cough or hoarseness
- diarrhea
- discouragement
- feeling sad or empty
- fever
- high fever
- irritability
- itching
- joint or muscle pain
- lack of appetite
- loss of interest or pleasure
- lower back or side pain
- mood or mental changes
- nervousness
- painful or difficult urination
- pale skin
- red skin lesions, often with a purple center
- red, irritated eyes
- shakiness and unsteady walk
- shortness of breath
- sore throat
- sores, ulcers, or white spots on the lips or in the mouth
- swelling around the eyes
- swollen glands
- tiredness
- trouble with concentrating
- trouble with sleeping
- unexplained bleeding or bruising
- unsteadiness, trembling, or other problems with muscle control or coordination
- unusual bleeding or bruising
- unusual tiredness or weakness
- vision changes
Get emergency help immediately if any of the following symptoms of overdose occur while taking methsuximide:
Symptoms of overdose
- Change in consciousness
- difficult or troubled breathing
- irregular, fast or slow, or shallow breathing
- loss of consciousness
- pale or blue lips, fingernails, or skin
Other side effects of Celontin
Some side effects of methsuximide may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.
Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:
Incidence not known
- Blurred vision
- change in color vision
- difficulty having a bowel movement (stool)
- difficulty seeing at night
- dizziness
- drowsiness
- heartburn
- hiccups
- hives or welts
- increased sensitivity of the eyes to sunlight
- loss of appetite
- nausea or vomiting
- pain or discomfort in the chest, upper stomach, or throat
- redness of the skin
- skin rash
- sleeplessness
- unable to sleep
- weight loss
For Healthcare Professionals
Applies to methsuximide: oral capsule.
General
The more frequently reported adverse events have included gastrointestinal symptoms such as nausea, vomiting, and anorexia and neurologic reactions such as drowsiness, dizziness and headache.
Gastrointestinal
Frequency not reported: Nausea, vomiting, anorexia, diarrhea, weight loss, epigastric and abdominal pain, constipation, hiccups[Ref]
Nervous system
Frequency not reported: Drowsiness, ataxia, dizziness, headache[Ref]
Psychiatric
Rare (less than 0.1%): Psychosis, suicidal behavior, auditory hallucinations
Frequency not reported: Confusion, instability, mental slowness, depression, hypochondriacal behavior, aggressiveness, irritability, nervousness, insomnia.[Ref]
Hematologic
Frequency not reported: Eosinophilia, leukopenia, monocytosis, and pancytopenia with or without bone marrow suppression[Ref]
Ocular
Frequency not reported: Periorbital edema, blurred vision[Ref]
Genitourinary
Frequency not reported: Proteinuria, microscopic hematuria[Ref]
Cardiovascular
Frequency not reported: Hyperemia[Ref]
Dermatologic
Frequency not reported: Urticaria, Stevens-Johnson syndrome, pruritic erythematous rashes[Ref]
