Usual Adult Dose for Intraocular Hypertension

Instill 1 drop in the affected eye(s) once a day in the evening

Use: For the reduction of elevated intraocular pressure in patients with open-angle glaucoma or ocular hypertension

Usual Adult Dose for Glaucoma (Open Angle)

Instill 1 drop in the affected eye(s) once a day in the evening

Use: For the reduction of elevated intraocular pressure in patients with open-angle glaucoma or ocular hypertension

Renal Dose Adjustments

Data not available

Liver Dose Adjustments

Data not available

Precautions

Safety and efficacy have not been established in patients younger than 18 years.

Consult WARNINGS section for additional precautions.

Dialysis

Data not available

Other Comments

Administration advice:

• If a dose is missed, treatment should continue with the next dose in the evening.
• Twice a day dosing is not well tolerated and not recommended.
• If used concomitantly with other topical ophthalmic drug products to lower intraocular pressure, administer each drug at least 5 minutes apart.

• Store at 2C to 8C (36F to 46F) until opened; after opening, may be kept at 2C to 25C (36F to 77F) for up to 6 weeks.
• During shipment, the bottle may be maintained at temperatures up to 40C (104F) for a period not exceeding 14 days.

• Avoid allowing the tip of the dispensing container to come into contact with the eye, surrounding structures, fingers, or any other surface in order to avoid contamination of the solution by common bacteria known to cause ocular infections; serious damage to the eye and subsequent loss of vision may result from using contaminated solutions.
• If a new ocular condition (e.g., trauma or infection) develops, ocular surgery occurs, or you develop any ocular reactions, particularly conjunctivitis and eyelid reactions, immediately seek your physician's advice concerning continued use.
• Contact lenses should be removed prior to administration and may be reinserted 15 minutes following administration.
• If a dose is missed, treatment should continue with the next dose in the evening.
• If used concomitantly with other topical ophthalmic drug products to lower intraocular pressure, administer each drug at least 5 minutes apart.