Uses of Bionect:

• It is used to promote healing of skin ulcers and wounds.
• It may be given to you for other reasons. Talk with the doctor.

What do I need to tell my doctor BEFORE I take Bionect?

• If you have an allergy to hyaluronic acid or any other part of Bionect (hyaluronate sodium cream, gel, and spray).
• If you are allergic to Bionect (hyaluronate sodium cream, gel, and spray); any part of Bionect (hyaluronate sodium cream, gel, and spray); or any other drugs, foods, or substances. Tell your doctor about the allergy and what signs you had.
• If you are using a product that contains ammonium salts or chlorhexidine to clean the area.

This is not a list of all drugs or health problems that interact with Bionect (hyaluronate sodium cream, gel, and spray).

Tell your doctor and pharmacist about all of your drugs (prescription or OTC, natural products, vitamins) and health problems. You must check to make sure that it is safe for you to take Bionect (hyaluronate sodium cream, gel, and spray) with all of your drugs and health problems. Do not start, stop, or change the dose of any drug without checking with your doctor.

What are some things I need to know or do while I take Bionect?

• Tell all of your health care providers that you take Bionect (hyaluronate sodium cream, gel, and spray). This includes your doctors, nurses, pharmacists, and dentists.
• Tell your doctor if you are pregnant, plan on getting pregnant, or are breast-feeding. You will need to talk about the benefits and risks to you and the baby.

How is this medicine (Bionect) best taken?

Use Bionect (hyaluronate sodium cream, gel, and spray) as ordered by your doctor. Read all information given to you. Follow all instructions closely.

• Do not take Bionect (hyaluronate sodium cream, gel, and spray) by mouth. Use on your skin only. Keep out of your mouth, nose, and eyes (may burn).
• Wash your hands before and after use. Do not wash your hands after use if putting this on your hand.
• Clean affected part before use. Make sure to dry well.
• Put a thin layer on the affected skin.
• Cover the wound with a clean dressing.
• Do not use Bionect (hyaluronate sodium cream, gel, and spray) for longer than you were told by your doctor.
• Talk with your doctor before you use other drugs or products on your skin.

What do I do if I miss a dose?

• Put on a missed dose as soon as you think about it.
• If it is close to the time for your next dose, skip the missed dose and go back to your normal time.
• Do not put on 2 doses at the same time or extra doses.

What are some side effects that I need to call my doctor about right away?

WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Tell your doctor or get medical help right away if you have any of the following signs or symptoms that may be related to a very bad side effect:

• Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing, swallowing, or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat.

What are some other side effects of Bionect?

All drugs may cause side effects. However, many people have no side effects or only have minor side effects. Call your doctor or get medical help if any of these side effects or any other side effects bother you or do not go away:

• Irritation where Bionect (hyaluronate sodium cream, gel, and spray) is used.

These are not all of the side effects that may occur. If you have questions about side effects, call your doctor. Call your doctor for medical advice about side effects.

You may report side effects to the FDA at 1-800-332-1088. You may also report side effects at https://www.fda.gov/medwatch.

If OVERDOSE is suspected:

If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.

How do I store and/or throw out Bionect?

• Store at room temperature. Do not freeze.
• Be sure you know how long you can store Bionect (hyaluronate sodium cream, gel, and spray) before you need to throw it away.
• Store in a dry place. Do not store in a bathroom.
• Keep all drugs in a safe place. Keep all drugs out of the reach of children and pets.
• Throw away unused or expired drugs. Do not flush down a toilet or pour down a drain unless you are told to do so. Check with your pharmacist if you have questions about the best way to throw out drugs. There may be drug take-back programs in your area.

Consumer Information Use and Disclaimer

• If your symptoms or health problems do not get better or if they become worse, call your doctor.
• Do not share your drugs with others and do not take anyone else's drugs.
• Some drugs may have another patient information leaflet. Check with your pharmacist. If you have any questions about Bionect (hyaluronate sodium cream, gel, and spray), please talk with your doctor, nurse, pharmacist, or other health care provider.
• If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.